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Despite their heterochromatic state, telomeres are able to be actively transcribed resulting in a production of long non-coding RNAs called TERRA (telomeric repeat-containing RNA)

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Can sterile water be used to reconstitute TB-500

Gene Activation: MC1R activation initiates a signaling cascade (cAMP production $\rightarrow$ MITF expression) that induces the enzymes (tyrosinase) necessary for eumelanin production

Storage conditions: Keep the container in a dry, cool place away from light

Most chemicals cannot be expedited