B12 deficiency is associated with depression, cognitive impairment, irritability, and in severe cases, psychosis
Its impact on inactivation of mitochondrial proteins depends on the level of generation in mitochondria
Journal of Applied Physiology 110(3):774-780
February 2002
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Side effects are minimal and typically limited to temporary redness, mild stinging, or irritation at the subcutaneous injection site, which subsides quickly