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Implication: This could be promising for individuals with IBD or leaky gut symptoms, though human studies are still needed
AOD-9604 adds a tyrosine residue at the N-terminus relative to the raw HGH 177-191 sequence, making it a 16-mer rather than a 15-mer
Pregnant or breastfeeding women safety unknown Cancer patients or those with tumor history due to VEGF promotion, angiogenesis could theoretically support tumor growth Autoimmune disorders while BPC-157 is generally anti-inflammatory, immune modulation can vary by individual Angiogenic peptides may pose theoretical risks in neoplastic conditions by promoting blood vessel formation
Phase 2 trial - Lancet, 2023 Liver fat (fatty-liver disease) Liver fat measured by MRI in people with fatty-liver disease - the trial behind the -82.4% figure
It stimulates lipolysis (the breakdown of fat) and inhibits lipogenesis (the formation of new fat)
Growth factor receptor interaction studies: Characterizing interactions with GH and IGF-1 receptor pathways in cell-based assays and tissue explant models
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