Tirzepatide works similarly, though it targets both GLP-1 and GIP receptors, which means it can have an even greater effect on blood sugar levels and weight loss
Similarly, people with cystic fibrosis often have weight loss due to malabsorption of nutrients, along with intestinal inflammation
Waikar SS, Wald R, Chertow GM, Curhan GC, Winkelmayer WC, Liangos O, et al
They result from the formation of hydrogen sulfide gas in the digestive tract
Example in development - Triple agonists targeting GLP-1, GIP, and glucagon are in early trials
Complications include malnutrition, fatigue, weight loss, vitamin deficiencies, intestinal obstruction due to bezoars, and small intestinal bacterial overgrowth