Small human studies support the biological plausibility of both approaches, but there are no robust head-to-head clinical trials proving that one produces better health outcomes than the other
In this review, the mechanisms underlying the hyperammonemia and neurological dysfunction in urea cycle disorders, organic acidurias, and fatty acids oxidation defects, as well as the therapeutic strategies for the ammonia control will be discussed
doi: 10.1056/NEJMoa2209254, 35 DexterD.CarterC.AgidF.AgidY.LeesA
Traditional Chinese medicine usually contains a variety of active components, which can produce additive or synergistic effects at the same time
Preclinical animal studies raise concerns about reproductive toxicity, whereas emerging human data suggest no significant increase in major congenital malformations compared with insulin
Keeping out of the sun for long periods of time should also be a priority