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Does cagrilintide preserve muscle mass better than retatrutide

Both #semaglutide and #tirzepatide demonstrate significant reductions in HF hospitalization and mortalityyet the lack of incremental benefit with tirzepatide over semaglutide raises key questions about mechanism of action, dose-response, and patient selection

The additional GIP receptor activation provides a genuinely new mechanism, not just a reset of the same one

Resistance training and adequate protein intake can reduce muscle loss during semaglutide treatment, but they cannot eliminate it entirely

Tirzepatide works differently than many older diabetes medicines

HLH across Speciality collaboration, UK