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Heavy drinkers with depressive symptoms typically exhibit (1) later age of MDD onset (post-25 years), (2) predominance of somatic symptoms (e.g., fatigue, insomnia) over cognitive rumination, and (3) partial responsiveness to selective serotonin reuptake inhibitors (SSRIs), which may reflect underlying serotonergic deficits compounded by ethanols neurotoxic effects (Pedrelli et al

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Plant foods contain effectively zero bioavailable B12

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These amino acids work together to neutralize free radicals, reduce oxidative stress, and support immune function