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Chronically-elevated leptin levels are associated with obesity, overeating, and inflammation-related diseases including type 2 diabetes, cardiovascular diseases, and yet again osteoporosis

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Direction of transfer is a property of the system, not of the vial

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In summary, these studies highlight microglial polarization modulation as a central therapeutic approach in PD, targeting both inflammatory response and iron-dependent oxidative damage to confer neuroprotection