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Central anorexigenic actions of bile acids are mediated by TGR5
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Figure 3 On the other hand, immunohistochemical studies in mice may show a strong GLP-1 expression in specific subsets of taste bud cells, mainly in circumvallate and fungiform papillae, and approximately 10% of all taste cells are GLP-1 positive, possibly meaning a strong relationship with taste perception as they co-express -gustducin, a G protein associated with the transduction of sweet, umami, and bitter tastes