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10.3390/jcm9030741 16 Bosma-den BoerM
Morikiri Y, Matsuta E, Inoue H
The main therapeutic mechanism of PDT is that photosensitizers were employed to convert oxygen into highly cytotoxic singlet oxygen ( 1 O 2 ), OH, and so on under light irradiation, thus causing irreversible damage to tumor tissue
Naderi GA, Asgari S, Taher M
Moreover, oxidative stress makes the kidney tissue susceptible to damage by various alterations including the promotion of lipid peroxidation, protein modification, and DNA damage, leading to cell death [14]
In brief, Pt-associated transporter proteins determine the accumulation of Pt drugs in DRG and, thus, could be developed as therapeutic targets to prevent the development of PIPN
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