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GLP-1 medications are a powerful example, offering benefits beyond blood sugar control

Dixon et al., 2007)

If you need ongoing motivation and accountability to stay on track, that lack of personal coaching can make weight regain more likely, and other programs like Calibrate or WeightWatchers may be a better fit

But lowering doses too much may reduce effectiveness, says Pinto, adding there needs to be a steady concentration of GLP-1s in the bloodstream for them to work

Like the ADA, the AACE/ACE algorithm recommends intensification from monotherapy to dual therapy and beyond for patients not achieving glycemic goals after 3 months of therapy with a given antihyperglycemic regimen

Highlights Semaglutide protects against cyclophosphamide-induced peripheral neuropathy by restoring motor coordination and sensory function in rats