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In fasted healthy normal weight patients, GLP-1 (7-36) amide injection reduced fMRI activity induced by food images, in all brain areas studied (amygdala, insula, caudate, NAc, orbitofrontal cortex, and putamen), compared to saline injection [43]
Racial and genomic determinants In a nationwide retrospective cohort study, Tabernacki et al
The glucagon component, which makes retatrutide fundamentally different from semaglutide and tirzepatide , is what makes retatrutide unique among GLP-1 class medications, and it is also what makes the side effect profile slightly different
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