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Research shows GLP-1 receptor agonists effectively reduce visceral fat, though whether this reduction is preferential compared to subcutaneous fat continues to be investigated

Insulin and sulfonylureas (gliclazide, glimepiride) used in diabetes management promote weight gain by reducing glycosuria and increasing cellular glucose uptake

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The genomic loci of rv1127c is adjacent to genes that encode essential enzymes of the methylcitrate cycle (MCC) (methylcitrate synthase (MCS and Rv1131c) and methylcitrate dehydratase (MCD and Rv1130c) and their transcriptional regulator (PrpR and Rv1129c) (Fig