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The reminder that even after the acne finally cleared, it left its mark
Discontinuations of one or two years without resuming GLP-1 use resulted in a 14% or 22% increased risk of cardiovascular events, respectively, compared to staying on the drugs
The strong association between sleep-related impairment and self-reported fatigue severity suggests that the increased fatigue in the +ADT group may be due to sleep dysfunction
It is a nonapeptide associated with the regulation of sleep-wake cycles and neuroendocrine function
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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