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This depends on the patients kidney health and overall condition

Visual inspection is your first line of defense

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Ascorbic Acid (Vitamin C) Injection Ascorbic Acid (Vitamin C) Injection (Preservative Free) (30 mL Vial) Ascorbic Acid (Vitamin C) Injection (Preserved) (30 mL Vial) Product Overview Ascorbic Acid (Vitamin C) Injection is a compounded sterile injectable solution formulated for parenteral administration, designed to deliver high concentrations of vitamin C directly into the bloodstream

Once your levels stabilize, you may only have to get injections less often to keep your levels reasonable

The cycling protocols commonly recommended are partly based on this theoretical concern, though actual tolerance development has not been documented