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Follow-up care : Ask about follow-up care in case of any concerns or complications after the treatment
N.FieldsR
The titration regimen described in the NEJM 2023 obesity trial (Jastreboff et al.) progressed as follows: Weeks 14 : 2 mg once weekly Weeks 58 : 4 mg once weekly Weeks 912 : 8 mg once weekly Week 12 onwards : Up to 12 mg once weekly (in higher-dose cohorts) This regimen was used exclusively within a regulated clinical trial setting and does not constitute an approved dosing schedule
They act on completely different receptor pathways to produce the same end result (growth hormone release)
K.EricksonK
Prescription DPP-4 inhibitors like sitagliptin extend GLP-1 half-life by blocking this enzyme, approximately doubling circulating GLP-1 levels
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