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Studies found that intrathecal injection of GLP-1RAs effectively reduced formalin-induced peripheral nerve injury, as well as cancer- and diabetes-induced pain without causing serious adverse reactions
Semaglutide sc Once-Weekly in Type 2 Diabetes: A Population Pharmacokinetic Analysis
They just solve the problem in almost opposite ways
Both semaglutide and tirzepatide are designed for steady, sustained results rather than rapid drops, which is part of why ongoing monitoring matters
[Accessed 16th April 2026]
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