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Common indications include: Pernicious anaemia an autoimmune condition where the stomach cannot produce intrinsic factor, a protein necessary for B12 absorption [8] [9] Malabsorption disorders including Crohn's disease, coeliac disease, or following gastric surgery Strict vegan or vegetarian diets with confirmed deficiency though high-dose oral B12 may be sufficient if no malabsorption exists Certain medications such as metformin or proton pump inhibitors that may interfere with B12 absorption [9] [10] Neurological symptoms including peripheral neuropathy, memory problems, or balance difficulties related to deficiency Diagnosis should be confirmed through blood tests measuring serum B12 levels, full blood count, folate, and often anti-intrinsic factor antibodies
JAMA, 302(19), 21192126
Others take longer, and if B12 wasnt the cause, you may notice little change
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To investigate the transcriptomic changes induced by Gclc deletion, we performed downstream analyses of FoB (Supplementary Fig
Handling & Use (Laboratory Settings) Intended Use: Research use only
