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Real pharmacological activity produces real gastrointestinal effects
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However, the most common presentation of CP-induced nephrotoxicity is acute kidney injury (AKI) (Miller et al., 2010), which is characterized by the rapid decline of renal excretory function leading to the accumulation of nitrogenous waste products, water, and electrolytes (Ostermann and Joannidis, 2016
doi: Bigio, B., Azam, S., Math, A.A
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