Mater Adv (2021) 2(6):182171
Excipient studies on lyophilized rhGH show that sugar and polyol stabilizers (mannitol, sucrose, trehalose) protect the protein's secondary structure and limit aggregation in the dry state by satisfying water-binding sites and stabilizing the amorphous matrix around the protein (Costantino et al., 1998)
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2021), while such processes can also generate problematic gaseous emissions including volatile organic compounds, SO x , and NO x (Wedrychowicz et al
A well-functioning immune system relies on adequate levels of glutathione to help combat infections and inflammation