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Its registered CV primary is broader than classic 3-point MACE it includes heart-failure events (hospitalization or urgent HF visit) alongside CV death, non-fatal MI, and non-fatal stroke

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Some research suggests that individuals with specific COMT gene polymorphisms (particularly the val/val genotype) might experience different metabolic responses to green tea consumption, though this evidence remains preliminary and heterogeneous

PLEASE NOTE: Clinical trials have indicated that Retatrutide may lead to greater average weight loss than tirzepatide, another dual-agonist medication, although retatrutide is still investigational and not yet FDA-approved

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Neurosci Lett 2014