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So what we assume that the glutathione was actually getting broken down, the cysteine was getting reabsorbed, and we're getting used to produce glutathione again
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Kremer et al., 2024) with an indispensable role of STAT3 activation due to methylation at a CpG site in the GFAP promoter (Takizawa et al., 2001), and in TET1/2/3-mediated DNA demethylation for establishing neural stem cell identity and enabling glial (e.g., astrocyte and oligodendrocyte) differentiation (MacArthur et al., 2024)
doi: 10.1016/j.phymed.2008.12.011 174 MartinetW.CoornaertI.PuylaertP.De MeyerG