in a retrospective observational study where they showed that two-thirds of weight regain following bariatric surgery can be lost with GLP-1 RAs treatment with only mild, transient and mostly GI-related adverse events reported in one-third of patients (57)
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95,99 Activation of Y 2 leads to lower NPY release and higher -MSH release
It also indirectly inhibits bone resorption through calcitonin release from thyroid C-cells