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Proc Natl Acad Sci USA 1995
Plant-derived flavonoids are a potential source of drugs for the treatment of liver fibrosis
In a final volume of 1 mL, 650 L neutralized supernatant, 330 L of 100 mM sodium dihydrogen phosphate buffer (pH 7.0), and 20 L freshly prepared 0.5 M N-acetyl-L-cysteine were added and incubated for 10 min, after which the optical density was recorded at 288 nm
Ingested -carotene can be cleaved in the lumen of the intestine by either of two -carotene oxygenases (-carotene-15,15-monooxygenases) encoded by the BCO1 and BCO2 genes to yield two molecules of retinaldehyde (retinal)
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Hansen JC, Deguchi Y
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