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Patients on levothyroxine should have thyroid function monitored after initiating tirzepatide and following dose increases, as adjustments to levothyroxine dosing may be necessary
The study received no outside funding
The SELECT cardiovascular trial [2] confirmed these microbiome changes persist long-term, with sustained alterations in bile acid metabolism affecting gut bacterial composition even after 2 years of treatment at the 2 Easing constipation: Constipation is one of the most common semaglutide side effects
doi: 10.1016/j.ygeno.2012.11.009 48 LiSZQiaoSFZhangJHLiK
BMJ Open 14 , e074391 (2024)
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