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The answer isnt one-size-fits-allit depends on the severity of the deficiency, the treatment method, and how well your body responds

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-glutamyl kinase (GK) encoded by PRO1 in eukaryotes or proB in prokaryotes, the first enzyme in proline biosynthetic pathway, catalyzes the formation of intermediate -glutamyl phosphate, which if accumulated could partially react with cysteine to generate -GC, and then Gsh2 adds glycine to -GC to form GSH

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Mechanism in research literature NNMT (nicotinamide N-methyltransferase) catalyses the methylation of nicotinamide using S-adenosylmethionine (SAM) as the methyl donor, producing 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine