Elevated cortisol levels increase gluconeogenesis in the liver, impair insulins ability to translocate GLUT4 to the cell surface, and raise portal and peripheral free fatty acids [72, 73]
This effect was observed in human umbilical vein endothelial cells treated with exendin-4 [67]
Similarly, Mn has also been utilized in the fabrication of TCPP-based MOFs to consume the intracellular GSH
PubMed Duzel, A., Vlainic, J., Antunovic, M., Malekinusic, D., Vrdoljak, B., Samara, M., Gojkovic, S., Krezic, I., Vidovic, T., Bilic, Z., Sjekavica, I., Djuzel, A.R., Knezevic, M., Sever, A.Z., Lojo, N., Kokot, A., Sever, M., Drmic, D., Seiwerth, S., Sikiric, P
and Parker, P
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