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Using biological enzymes as carriers is a good choice because they have good biocompatibility and low toxicity

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It works by blocking an enzyme called NNMT (nicotinamide N-methyltransferase)

Finerenone, a novel non-steroidal selective MR antagonist (MRA), demonstrates fewer adverse effects on serum potassium levels and renal function compared to steroidal MRAs which have been approved by FDA for treatment of DKD (208)

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