The first case involves a 54-year-old man who, about one month after starting semaglutide, experienced a marked decline in energy, motivation, fatigue, difficulty concentrating, and mood disturbances
The substance remains available as a research-grade chemical reference compound
The FDA found BPC-157, inadequately characterised, historical compounding data limited, safety and immunogenicity insufficiently defined, and evidence inadequate to establish effectiveness
However, existing chemotherapeutic medicines are associated with significant toxicities and are not highly effective in killing cancer cells
doi:10.1136/bmjopen-2024-086454 Manthey J, Hassan SA, Carr S, Kilian C, Kuitunen-Paul S, Rehm J
Effect of increasing doses of recombinant human insulin-like growth factor-I on glucose, lipid, and leucine metabolism in man