It's probable all those Multiverse Legends are skewing things, since every pack has one, and more of them are first-pickable than BRO's Retro Artifacts
Other Octopus token generators include Fisher's Talent, Octomancer, and the Kiora, Master of the Depths emblem
The more counters you put on Hancock, the bigger all of your other Mutants and Zombies get
That means that I'm not going to take into account the possible infinite combos or insane synergies cards may have with other, specific cards in the game
Try to follow along at home
Infect commanders generally revolve around proliferate or poison counters directly, or combat to allow for creatures with infect to attack the opponent directly, oftentimes finding ways around potential blockers