Of the four cards in the drop which also includes Mystic Remora, Retreat to Coralhelm and Burgeoning its Utopia Sprawl that stands out to us
We want our opponents to beat each other to death quickly, while using up their resources to answer each others boards so that we can build up our own resources quietly until the endgame
This is bad in a lot of decks, but in can be good in a couple scenarios: one of these is that your deck is incredibly aggressive, and Act of Treason can consistently end games for you
Harvester of Misery looks like a shoe-in for any high-powered Cube with a Reanimator theme, as well as a solid option for Control decks assuming that -2/-2 isnt too oppressive against the aggressive decks in your environment
One such archetype that my playgroup almost instantly regretted letting me try was the infamous strategy known as Infect
Single-target pump spells are rarely seen in Commander outside of Poison decks, because their effect - helping a single creature win a single combat - is so small compared to the infinite combos, massive token armies, and other nonsense that the format is known for