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You can play more than 40 cards, but I would strongly advise against it: every card you play beyond 40 just worsens the odds of drawing your best cards

#3 Tithe There arent many cards in the game that can draw two cards for one mana, and Tithe can do that at instant speed

Being a threat or value as the game demands is an effect you want in your cubes as they will make games more consistent and enjoyable

Then, Save

There are more in the way of four drop lords but it is all a bit too much at that point

Qli are all about Pendulum Summoning a bunch of Monsters onto the field, and then tribute summoning their main Boss Monsters